Symbol
Name
ID

Prickle1
prickle planar cell polarity protein 1
MGI:1916034

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Sensory axonal neuropathy	Ataxia	Dysmetria	Myoclonus	Tremor	Babinski sign	Dysarthria	Generalized myoclonic seizure	Atonic seizure
Disease(s) Associated with PRICKLE1
progressive myoclonus epilepsy 1B

Mouse Phenotypes

increased susceptibility to pharmacologically induced seizures

abnormal seizure response to electrical stimulation

delayed neural tube closure

abnormal cochlear hair cell stereociliary bundle morphology

short cochlear hair cell stereocilia

enlarged lateral ventricles

abnormal striatum morphology

abnormal hippocampus morphology

abnormal innervation

abnormal nervous system tract morphology

abnormal excitatory synapse morphology

Availability

Mouse Genotype

Prickle1^em1Yzou/Prickle1^em1Yzou

Prickle1^tm1.2Asw/Prickle1^tm1.2Asw

Prickle1^em1Yzou/Prickle1⁺

Prickle1^m1Ingm/Prickle1⁺

Prickle1^m2Ingm/Prickle1⁺

Prickle1^tm1Nue/Prickle1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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